On Oscillations in a Gene Network with Diffusion Full article
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Mathematics
, E-ISSN: 2227-7390 |
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| Output data | Year: 2023, Volume: 1951, Number: 11, Article number : 11-01951, Pages count : 12 DOI: 10.3390/math11081951 | ||
| Tags | gene network models; phase portraits; systems of non-linear differential equations; reaction–diffusion equations; cycles; stability; invariant surfaces; invariant domains; Poincaré map; fixed point theorem | ||
| Authors |
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| Affiliations |
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Funding (1)
| 1 | Russian Science Foundation | 23-21-00019 |
Abstract:
We consider one system of partial derivative equations of the parabolic type as a model of a simple 3D gene network in the presence of diffusion of its three components. Using discretization of the phase portrait of this system, comparison theorems, and other methods of the qualitative theory of differential equations, we show uniqueness of the equilibrium solution to this system and find conditions of instability of this equilibrium. Then, we obtain sufficient conditions of existence of at least one oscillating functioning regime of this gene network. An estimate of lower and upper bounds for periods of these oscillations is given as well. In quite a similar way, these results on the existence of cycles in 3D gene networks can be extended to higher-dimensional systems of parabolic or other evolution equations in order to construct mathematical models of more complicated molecular genetic systems
Cite:
Golubyatnikov V.
, Ayupova N.
, Kirillova N.
On Oscillations in a Gene Network with Diffusion
Mathematics. 2023. V.1951. N11. 11-01951 :1-12. DOI: 10.3390/math11081951 WOS Scopus РИНЦ OpenAlex
On Oscillations in a Gene Network with Diffusion
Mathematics. 2023. V.1951. N11. 11-01951 :1-12. DOI: 10.3390/math11081951 WOS Scopus РИНЦ OpenAlex
Dates:
| Submitted: | Mar 16, 2023 |
| Published print: | Apr 20, 2023 |
| Published online: | Apr 20, 2023 |
Identifiers:
| Web of science: | WOS:000976444200001 |
| Scopus: | 2-s2.0-85153760574 |
| Elibrary: | 61380809 |
| OpenAlex: | W4366773860 |