Central Regulatory Circuit of the Drosophila Mechanoreceptor Morphogenesis System: Effects of Mutations Full article
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Journal of Applied and Industrial Mathematics
ISSN: 1990-4789 , E-ISSN: 1990-4797 |
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| Output data | Year: 2023, Volume: 17, Number: 3, Pages: 535-543 Pages count : 9 DOI: 10.1134/S1990478923030079 | ||||||
| Tags | central regulatory circuit, gene network, mathematical model, parameter identification, computer modeling, Drosophila, achaete-scute complex, mutation | ||||||
| Authors |
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| Affiliations |
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Funding (2)
| 1 | Sobolev Institute of Mathematics | FWNF-2022-0009 |
| 2 | Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences | FWNR-2022-0020 |
Abstract:
We describe a mathematical model of the functioning of the central regulatory circuit of gene networks for the morphogenesis of Drosophila mechanoreceptors taking into account mutations of the genes included in it. Computational experiments have been carried out showing the existence of a hierarchy of effects of CRC gene mutations on the production of ASC proteins.
Cite:
Furman D.P.
, Bukharina T.A.
, Golubyatnikov V.P.
Central Regulatory Circuit of the Drosophila Mechanoreceptor Morphogenesis System: Effects of Mutations
Journal of Applied and Industrial Mathematics. 2023. V.17. N3. P.535-543. DOI: 10.1134/S1990478923030079 Scopus РИНЦ OpenAlex
Central Regulatory Circuit of the Drosophila Mechanoreceptor Morphogenesis System: Effects of Mutations
Journal of Applied and Industrial Mathematics. 2023. V.17. N3. P.535-543. DOI: 10.1134/S1990478923030079 Scopus РИНЦ OpenAlex
Original:
Фурман Д.П.
, Бухарина Т.А.
, Голубятников В.П.
Центральный регуляторный контур системы морфогенеза механорецепторов дрозофилы: эффекты мутаций
Сибирский журнал индустриальной математики. 2023. Т.26. №3. С.142-153. DOI: 10.33048/SIBJIM.2023.26.311 РИНЦ
Центральный регуляторный контур системы морфогенеза механорецепторов дрозофилы: эффекты мутаций
Сибирский журнал индустриальной математики. 2023. Т.26. №3. С.142-153. DOI: 10.33048/SIBJIM.2023.26.311 РИНЦ
Dates:
| Submitted: | Feb 9, 2023 |
| Accepted: | Apr 27, 2023 |
| Published online: | Sep 20, 2023 |
| Published print: | Nov 4, 2023 |
Identifiers:
| Scopus: | 2-s2.0-85175822228 |
| Elibrary: | 64003596 |
| OpenAlex: | W4388337428 |
Citing:
| DB | Citing |
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| Elibrary | 1 |