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Machine Learning and Deep Learning Models for Nocturnal High- and Low-Glucose Prediction in Adults with Type 1 Diabetes Full article

Journal Diagnostics
ISSN: 2075-4418
Output data Year: 2024, Volume: 14, Number: 7, Article number : 740, Pages count : 12 DOI: 10.3390/diagnostics14070740
Tags type 1 diabetes; continuous glucose monitoring; glucose range; prediction; machine learning; deep learning; neural networks; random forest; boosting trees
Authors Kozinetz Roman M. 1 , Berikov Vladimir B. 1 , Semenova Julia F. 1 , Klimontov Vadim V. 1
Affiliations
1 Laboratory of Endocrinology, Research Institute of Clinical and Experimental Lymphology-Branch of the

Funding (1)

1 Russian Science Foundation 20-15-00057

Abstract: Glucose management at night is a major challenge for people with type 1 diabetes (T1D), especially for those managed with multiple daily injections (MDIs). In this study, we developed machine learning (ML) and deep learning (DL) models to predict nocturnal glucose within the target range (3.9–10 mmol/L), above the target range, and below the target range in subjects with T1D managed with MDIs. The models were trained and tested on continuous glucose monitoring data obtained from 380 subjects with T1D. Two DL algorithms—multi-layer perceptron (MLP) and a convolutional neural network (CNN)—as well as two classic ML algorithms, random forest (RF) and gradient boosting trees (GBTs), were applied. The resulting models based on the DL and ML algorithms demonstrated high and similar accuracy in predicting target glucose (F1 metric: 96–98%) and above-target glucose (F1: 93–97%) within a 30 min prediction horizon. Model performance was poorer when predicting low glucose (F1: 80–86%). MLP provided the highest accuracy in low-glucose prediction. The results indicate that both DL (MLP, CNN) and ML (RF, GBTs) algorithms operating CGMdatacanbeused for the simultaneous prediction of nocturnal glucose values within the target
Cite: Kozinetz R.M. , Berikov V.B. , Semenova J.F. , Klimontov V.V.
Machine Learning and Deep Learning Models for Nocturnal High- and Low-Glucose Prediction in Adults with Type 1 Diabetes
Diagnostics. 2024. V.14. N7. 740 :1-12. DOI: 10.3390/diagnostics14070740 WOS Scopus РИНЦ OpenAlex
Dates:
Submitted: Dec 27, 2023
Accepted: Mar 28, 2024
Published print: Mar 30, 2024
Published online: Mar 30, 2024
Identifiers:
Web of science: WOS:001200806800001
Scopus: 2-s2.0-85190275355
Elibrary: 65437742
OpenAlex: W4393356819
Citing:
DB Citing
OpenAlex 5
Web of science 2
Scopus 7
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