Mathematical and Numerical Modeling of the Pluripotency Gene Network Dynamics

Mathematical and Numerical Modeling of the Pluripotency Gene Network Dynamics Full article

Journal

Numerical Analysis and Applications
ISSN: 1995-4239

Output data

Year: 2025, Volume: 18, Number: 1, Pages: 36-43 Pages count : 8 DOI: 10.1134/S1995423925010033

Funding (1)

Russian Science Foundation

23-21-00019

We consider nonlinear dynamical systems as models of interaction of components of a gene network which regulates early stages of an embryonic stem cells state. A parametric analysis of these dynamical systems is performed in order to describe the (non)uniqueness and stability of their equilibriums. We have obtained a criterion of existence of periodic trajectories near these points and localized such oscillations on the phase portraits of dynamical systems which describe these processes. A special software for cloud numerical experiments with such systems has been elaborated.

Golubyatnikov V.P. , Tatarinova E.A.
Mathematical and Numerical Modeling of the Pluripotency Gene Network Dynamics
Numerical Analysis and Applications. 2025. V.18. N1. P.36-43. DOI: 10.1134/S1995423925010033 WOS Scopus РИНЦ OpenAlex

Голубятников В.П. , Татаринова Е.А.
Математическое и численное моделирование генной сети поддержания плюрипотентности стволовой клетки
Сибирский журнал вычислительной математики. 2025. Т.28. №1. С.37-46. DOI: 10.15372/SJNM20250103 РИНЦ OpenAlex

Submitted:	May 7, 2024
Accepted:	Sep 20, 2024
Published print:	Feb 25, 2025
Published online:	Feb 25, 2025

Web of science:	WOS:001447356800007
Scopus:	2-s2.0-105000422869
Elibrary:	80498291
OpenAlex:	W4408563982

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