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Accessing the impact of functional variants on human phenotypes by transcriptome analysis in individuals carrying different rSNP alleles Научная публикация

Конференция Cognitive Sciences, Genomics and Bioinformatics
06-10 июл. 2020 , Новосибирск
Сборник Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020
Сборник, IEEE. 2020. 300 c.
Вых. Данные Год: 2020, Номер статьи : 9214706, Страниц : 4 DOI: 10.1109/CSGB51356.2020.9214706
Ключевые слова 1000 Genomes Project; functional annotation; phenotypic outcome; rSNPs; transcriptome analysis
Авторы Korbolina E. 1 , Bryzgalov L. 1 , Postovalov S. 2 , Nedelko V. 3 , Berikov V. 3 , Merkulova T. 1
Организации
1 Institute of Cytology and Genetics, Laboratory of Gene Expression Regulation, Novosibirsk, Russian Federation
2 Novosibirsk State Technical University, Department of Theoretical and Applied Informatics, Novosibirsk, Russian Federation
3 Sobolev Institute of Mathematics, Data Analysis Lab, Novosibirsk, Russian Federation

Реферат: the problem of functional annotation of regulatory single nucleotide polymorphisms is considered. Previously we have identified 1476 human regulatory SNPs through an integrated epigenome and transcriptome analysis. Here we employed the analysis of differentially expressed genes in order to explore the extensive impact of these regulatory variants on the phenotypic landscape. © 2020 IEEE.
Библиографическая ссылка: Korbolina E. , Bryzgalov L. , Postovalov S. , Nedelko V. , Berikov V. , Merkulova T.
Accessing the impact of functional variants on human phenotypes by transcriptome analysis in individuals carrying different rSNP alleles
В сборнике Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020. – IEEE., 2020. – C.10-13. DOI: 10.1109/CSGB51356.2020.9214706 Scopus OpenAlex
Идентификаторы БД:
Scopus: 2-s2.0-85094827289
OpenAlex: W3091769390
Цитирование в БД: Пока нет цитирований
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